information

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Phage therapy is influenced by:

Phage therapy is influenced by:

Country :
the epidemiological situation is different from country to country in terms of circulating bacteria and bacteriophages. Example: a lytic phages from Italy may be no active on the same bacteria (genus and species) isolated from another country and vice versa.
Chronolability
Mutation rate
Phenotypical delay
Phage cocktail
My point of view

From Wikipedia


If the target host* of a phage therapy treatment is not
an animal the term "
biocontrol" (as in phage-mediated biocontrol of bacteria) is usually employed, rather than "phage therapy".

"In silico"

From:"Genomics,Proteomics and Clinical Bacteriology", N.Woodford and Alan P.Johnson

Phrase that emphasizes the fact that many molecular biologists spend increasing amounts of their time in front of a computer screen, generating hypotheses that can subsequently be tested and (hopefully) confirmed in the laboratory.

Wednesday 2 July 2014

What is the practical approach used by georgian Phage therapy centers for phage therapy?




"The secret is under the light"( the  procedures and the protocols deduced are simple)


From Eliava Institute




1-there is a bacteriophages  library.

2-there are 80 years of  work experience.

3-there is a precise list of bacteria where it is possible to apply phage therapy.


4-there is a precise list of human diseases and others fields where it is possible to administer phage therapy.



5-there is a specific protocol that start with the request of bacteria sample isolated from the patient.

6-Start the  phage matching for bacteria sample.



7-in seven days arrive the results of phage matching with two possibilities: positive or negative response.

8-phage will be grown in 2-3 weeks in case of positive response but there is not garantee  regarding the success of the  treatment.


From Phage Therapy Center

1-there are 80 years of  work experience.
2-there is a declaration about the working method.
3-there is a declaration regarding the capacity to treat Methicillin resistant Staphylococcus aureus


4-there is a  detailed list of human diseases classified in three groups where it is possible to administer phage therapy with success in comparison with antibiotics.




 5-there is a declaration about the possibility  for some infections for which new phages need to be developed.

6-there is a declaration about the time for developping  new phages 
 and a comment regarding the difficulties for this work.
 7-there are the indications and modalities about prophylaxis and treatment of  bacterial infections in surgery
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