information

Whoever comes in this website may find a hint

Phage therapy is influenced by:

Phage therapy is influenced by:

Country :
the epidemiological situation is different from country to country in terms of circulating bacteria and bacteriophages. Example: a lytic phages from Italy may be no active on the same bacteria (genus and species) isolated from another country and vice versa.
Chronolability
Mutation rate
Phenotypical delay
Phage cocktail
My point of view

From Wikipedia


If the target host* of a phage therapy treatment is not
an animal the term "
biocontrol" (as in phage-mediated biocontrol of bacteria) is usually employed, rather than "phage therapy".

"In silico"

From:"Genomics,Proteomics and Clinical Bacteriology", N.Woodford and Alan P.Johnson

Phrase that emphasizes the fact that many molecular biologists spend increasing amounts of their time in front of a computer screen, generating hypotheses that can subsequently be tested and (hopefully) confirmed in the laboratory.

Monday, 28 July 2014

Mycobacterium ulcerans by "In Silico"analysis. Step 2


*It is possible to show the genome map of Mycobacterium ulcerans, example by Bacmap:


Open Bacmap

Choose letter M

Choose Mycobacterium ulceransOpen Map , now the genome map is showing.
Remember :
COGs
means Clusters of Orthologous Groups of proteins. 

The genome is divided in COGs ( groups of proteins with different action).

CDS is the coding sequence or the portion of a nucleotide sequence that makes up the triplet codons that actually code for amino acids.


*By BuruList it is possible to get a lot of information on Mycobacterium ulcerans genes:

write in the window Gene name: mlsA1
open and the page is showing


Remember :

contig is a Group of cloned (copied) pieces of DNA representing overlapping regions of a particular chromosome.