information

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Phage therapy is influenced by:

Phage therapy is influenced by:

Country :
the epidemiological situation is different from country to country in terms of circulating bacteria and bacteriophages. Example: a lytic phages from Italy may be no active on the same bacteria (genus and species) isolated from another country and vice versa.
Chronolability
Mutation rate
Phenotypical delay
Phage cocktail
My point of view

From Wikipedia


If the target host* of a phage therapy treatment is not
an animal the term "
biocontrol" (as in phage-mediated biocontrol of bacteria) is usually employed, rather than "phage therapy".

"In silico"

From:"Genomics,Proteomics and Clinical Bacteriology", N.Woodford and Alan P.Johnson

Phrase that emphasizes the fact that many molecular biologists spend increasing amounts of their time in front of a computer screen, generating hypotheses that can subsequently be tested and (hopefully) confirmed in the laboratory.

Thursday, 19 June 2014

My point of view


I would like to clarify my opinion about Phage Therapy:


Efficacy

-Phage Therapy Efficacy follows a decreasing Gradient in the recovery chances.
Both Recovery Results and Phage Presence are linked to the anatomical Site where a Bacterial Infection is localized and active.

-This decreasing Efficacy Gradient starts from the infective processes on the external surface of the Body to the infective processes on the intestinal mucosa and , in the end, to the infective processes reached by bloodstream only.

When the infection site is localized on the skin we may have by Phage Therapy the best recovery chance.


                                                                           

 

                                                                              Limitation
 -Phage Therapy has a precise Application Range. At the moment the choice of Phage Treatment is limited.The Effectiveness of Bacteriophage compositions is conditioned by the chronolability.






                                                                                When
 -All cases where there is a Drug-Resistance Problem and when this resistance problem is insuperable by another antibiotic,Phage Therapy might be administered.