information

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Phage therapy is influenced by:

Phage therapy is influenced by:

Country :
the epidemiological situation is different from country to country in terms of circulating bacteria and bacteriophages. Example: a lytic phages from Italy may be no active on the same bacteria (genus and species) isolated from another country and vice versa.
Chronolability
Mutation rate
Phenotypical delay
Phage cocktail
My point of view

From Wikipedia


If the target host* of a phage therapy treatment is not
an animal the term "
biocontrol" (as in phage-mediated biocontrol of bacteria) is usually employed, rather than "phage therapy".

"In silico"

From:"Genomics,Proteomics and Clinical Bacteriology", N.Woodford and Alan P.Johnson

Phrase that emphasizes the fact that many molecular biologists spend increasing amounts of their time in front of a computer screen, generating hypotheses that can subsequently be tested and (hopefully) confirmed in the laboratory.

Sunday, 15 June 2014

Antibiotic resistance: a worldwide problem

From WHO document:
" ANTIMICROBIAL RESISTANCE,Global Report on surveillance"


 A post-antibiotic era—in which common infections and minor injuries can kill—far from being an apocalyptic fantasy, is instead a very real possibility for the 21st century.
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Escherichia coli: Resistance to third-generation cephalosporins
Escherichia coli: Resistance to fluoroquinolones
Klebsiella pneumoniae: Resistance to third-generation cephalosporins
Klebsiella pneumoniae: Resistance to carbapenems
Staphylococcus aureus: Resistance to methicillin (MRSA)
Streptococcus pneumoniae: Resistance, or non-susceptibility, to penicillin
Nontyphoidal Salmonella (NTS): Resistance to fluoroquinolones                                                                             
Shigella species: Resistance to fluoroquinolones
Neisseria gonorrhoeae: Decreased susceptibility to third-generation cephalosporins.