The main target where there is a good chance of success for phage therapy is the skin infection because in this situation there are few adverse factors.
From
The reasons are:
-easy medication
-easy check
- use of one Lytic Phage or Phage cocktail
-direct contact with bacteria
-no antibodies
- easy to remove phage by washing
-et cetera
In my old web site there is this document from :
that now is unobtainable.
Comment:
First we must test phage therapy in this clinical area (and after in the others)
We must consolidate the theory but also to put it into the practice
It is unsatisfactory to write on Phage therapy only for publications
Why the PhagoBurn project is started ? For the same reasons described above .
information
Whoever comes in this website may find a hint
Phage therapy is influenced by:
Phage therapy is influenced by:
Country : the epidemiological situation is different from country to country in terms of circulating bacteria and bacteriophages. Example: a lytic phages from Italy may be no active on the same bacteria (genus and species) isolated from another country and vice versa.
Chronolability
Mutation rate
Phenotypical delay
Phage cocktail
My point of view
Country : the epidemiological situation is different from country to country in terms of circulating bacteria and bacteriophages. Example: a lytic phages from Italy may be no active on the same bacteria (genus and species) isolated from another country and vice versa.
Chronolability
Mutation rate
Phenotypical delay
Phage cocktail
My point of view
From Wikipedia
If the target host* of a phage therapy treatment is not an animal the term "biocontrol" (as in phage-mediated biocontrol of bacteria) is usually employed, rather than "phage therapy".
"In silico"
From:"Genomics,Proteomics and Clinical Bacteriology", N.Woodford and Alan P.Johnson
Phrase that emphasizes the fact that many molecular biologists spend increasing amounts of their time in front of a computer screen, generating hypotheses that can subsequently be tested and (hopefully) confirmed in the laboratory.