information

Whoever comes in this website may find a hint

Phage therapy is influenced by:

Phage therapy is influenced by:

Country :
the epidemiological situation is different from country to country in terms of circulating bacteria and bacteriophages. Example: a lytic phages from Italy may be no active on the same bacteria (genus and species) isolated from another country and vice versa.
Chronolability
Mutation rate
Phenotypical delay
Phage cocktail
My point of view

From Wikipedia


If the target host* of a phage therapy treatment is not
an animal the term "
biocontrol" (as in phage-mediated biocontrol of bacteria) is usually employed, rather than "phage therapy".

"In silico"

From:"Genomics,Proteomics and Clinical Bacteriology", N.Woodford and Alan P.Johnson

Phrase that emphasizes the fact that many molecular biologists spend increasing amounts of their time in front of a computer screen, generating hypotheses that can subsequently be tested and (hopefully) confirmed in the laboratory.

Monday 27 April 2015

How to chose and to plan a project of Phage therapy

 By these information it is possible in short time  to establish   on paper if there are some chanches of success.

It is indispensable to know of:

1-Bacterial diseases
a-social impact of the disease
b-economic impact of the disease

c-pathogenesis of the disease
 
2-Aetiological bacterial agent
a- presence of lytic phages  for this bacterial agent
b- the best route for Phage administration for this disease

 

From this link (http://www.rightdiagnosis.com) there is a list of types of bacterial diseases (but it is not exhaustive).

3-Check
1-first public written communication year ( journal,internet et cetera)
2-years passed from the first communication
3-how many dedicated clinical studies ?

At this moment there is a strong incoherence among point 3(1) and points 3(2),3(3).

    Monday 6 April 2015

    The Guardian: outbreak of drug-resistant infection could kill 80,000 in UK, report warns

    Link
    “Much of modern medicine (for example, organ transplantation, bowel surgery and some cancer treatments) may become unsafe due to the risk of infection."

    “In addition, influenza pandemics would become more serious without effective treatments.”

    “If we don’t take action, in 20 years’ time we could be back in the 19th century where infections kill us as a result of routine operations.”

    Saturday 4 April 2015

    A way to treat bacterial infections with artificial viruses

    Link

    " Dr Farah and his colleagues, by contrast, are able to synthesise viruses from scratch, using off-the-shelf chemicals. They can thus design them precisely, down to the last atom".

    PhagoBurn:Phage therapy dossier